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☆ Meet the little people whose bodies may hold a key to longevity
▼ + stars: | 2024-04-30 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +10 min

Sandra TorresTorres has a rare disorder called Laron syndrome that is caused by a genetic mutation. “This is how powerful this mutation seems to be.”What is Laron syndrome? Laron syndrome is a recessive gene, so only those who receive a copy from each parent will be affected. The condition leads to extreme obesity, a trigger for diabetes, heart disease, cancer and other diseases. While technically overweight at 100 pounds (45.4 kilograms), she was in good health, with no signs of diabetes or heart disease.

Persons: Paola Castro Torres, ” Torres, Torres, “, ” Nathaly Paola Castro Torres, Sandra Torres Torres, ”, Valter Longo, Longo, Laron, Jaime Guevara, Aguirre, Guevara, ” Longo, ” Guevara, Andrew Freeman, Freeman, ” Hope, it’s Organizations: CNN, gerontology, University of Southern, of Endocrinology, Laron, Jewish Health Locations: Los Angeles, Quito, Ecuador, University of Southern California, Israel, Yemen, East, United States, Croatia, Ireland, Denver

☆ 3 Factors Keeping Americans From New Weight-Loss Drugs
▼ + stars: | 2023-08-04 | by ( Gina Kolata | More About Gina Kolata | ) www.nytimes.com time to read: +3 min

That’s the median weight loss experienced by people who take Wegovy, a drug from Novo Nordisk. Many patients started by taking Ozempic, a diabetes drug also by Novo Nordisk that led to weight loss as a side effect. Mounjaro, made by Eli Lilly and approved for treating diabetes, is expected to be approved soon for obesity. While price and insurance coverage pose problems for patients, health economists expect prices to come down as more drugs are approved and companies face competition. Medicare is forbidden by law to pay for weight-loss drugs, although there is an intense lobbying effort to change that.

Persons: Eli Lilly, David A, Eli Lilly’s, “, ”, Ania, Robert F, Kushner Organizations: Novo Nordisk, Duke University, Yale University, Northwestern University Feinberg School of Medicine, “ Locations: Novo

☆ The Risks of Taking Drugs Like Ozempic When You’re Over 65
▼ + stars: | 2023-07-17 | by ( Dani Blum | More About Dani Blum | ) www.nytimes.com time to read: +1 min

That’s particularly a concern for older adults, obesity medicine experts say. The more muscle someone over the age of 65 loses, the greater their risk of becoming frail or suffering a fracture or fall (which can be fatal in older adults). It is crucial for older adults to maintain muscle mass so that they can stay mobile and independent. Muscle mass naturally dwindles with age. Clinical trials on semaglutide, the active ingredient in Ozempic and Wegovy, have typically enrolled people in their 40s and 50s.

Persons: — you’re, Scott Hagan, Janice Jin Hwang Organizations: University of Washington, University of North Carolina School of Medicine

☆ HRT use by younger women linked to dementia, study says. Experts disagree
▼ + stars: | 2023-06-28 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +7 min

However, experts who treat and study menopause say the study is unable to draw a direct connection to later-life dementia and that the overall benefits of hormone replacement therapy, or HRT, far outweigh the risks for many patients. “One finding in the study was a link between dementia and the use of HRT for a very short time span, under a year. Researchers compared people with dementia who had used hormone therapy, even briefly, with those from the larger group who had not. The chance of being diagnosed with dementia went up with years spent on HRT, the study found. When women used 12 or more years of hormone therapy, the association with a diagnosis of dementia rose to 74%, Pourhadi said.

Persons: ”, Nelsan, Pauline Maki, David Curtis, Kejal, Kantarci, Andrea Lenzi, University of Rome La Sapienza, ” Pourhadi, Pourhadi, Maki, ” Maki, Susan Davis, Amanda Heslegrave, ” Heslegrave Organizations: CNN, Danish Dementia Research, Copenhagen University Hospital Rigshospitalet, University of Illinois, UCL Genetics Institute, University College London, Mayo Clinic, University of Rome La, University of Illinois’s Center for Research, Women’s, Monash University, Dementia Research Locations: Danish, Denmark, Chicago, neuroradiology, Rochester , Minnesota, Taiwan, Melbourne, Australia, London

☆ People on Drugs Like Ozempic Say Their ‘Food Noise’ Has Disappeared
▼ + stars: | 2023-06-21 | by ( Dani Blum | ) www.nytimes.com time to read: +3 min

Videos related to the subject “food noise explained” have been viewed 1.8 billion times on TikTok. When food noise fadesWendy Gantt, 56, said she first heard the term food noise on TikTok, where she had also learned about Mounjaro. Ozempic is more of a way to silence the food noise than anything else, she said. “It’s not like a magic drug that’s giving people an easy way out.”What causes food noise? There is no clinical definition for food noise, but the experts and patients interviewed for this article generally agreed it was shorthand for constant rumination about food.

Persons: Wendy Gantt, ”, “, Kelsey Ryan, hasn’t, It’s, Ryan, “ It’s, Robert Gabbay, Janice Jin Hwang Organizations: American Diabetes Association, University of North Carolina School of Medicine Locations: Ozempic, Canandaigua, N.Y

☆ Obesity changes the brain, with ‘no sign of reversibility,’ researchers find
▼ + stars: | 2023-06-12 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +7 min

“This study captures why obesity is a disease — there are actual changes to the brain,” said Apovian, who was not involved in the study. They wanted to know if that would be different in people with obesity compared to those of normal weight. At the same time, levels of dopamine rose in those at normal weight, signaling that the reward centers of the brain were also activated. Losing weight did not reset the brain in people with obesity, Serlie said. Until science answers these questions, the study emphasizes, once again, that weight stigma has no place in the fight against obesity, Serlie said.

Persons: ’ ”, Caroline Apovian, ”, Apovian, Sadaf, they’ve, “, Mireille Serlie, ” Faroof, ” Serlie, Farooqi, Serlie, it’s, ” Farooqi, ‘ Organizations: CNN, Harvard Medical School, Center, Weight Management, Wellness, Brigham, Women’s Hospital, BMI, University of Cambridge, Yale School of Medicine Locations: Boston, New Haven , Connecticut

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